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Best Oral Flea Medicine for Dogs

7 minutes to read| Updated for 2022
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20...
PetArmor FastCaps (nitenpyram) Oral Flea Control Medication, 25 lbs and Over, 6 count
Advantus (Imidacloprid) Chewable Flea Treatment for Small Dogs, 7 Count, 4-22 Pounds
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20...
PetArmor FastCaps (nitenpyram) Oral Flea Control Medication, 25 lbs and Over, 6 count
Advantus (Imidacloprid) Chewable Flea Treatment for Small Dogs, 7 Count, 4-22 Pounds
Best for Medium Dogs
Best Tablet for Large Dogs
Best Soft Chew for Small Dogs
$75.98
Price not available
$28.98
Full-scope protection from a variety of pests in a matter of minutes.
For larger dogs, different levels of medication are necessary. This dose will get the job done. It will kill. However, it won’t protect.
Soft chews are a much more pleasant way to feed medicine to your dog. We love this formula and how much dogs love it.
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20...
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20...
Best for Medium Dogs
$75.98
Full-scope protection from a variety of pests in a matter of minutes.
PetArmor FastCaps (nitenpyram) Oral Flea Control Medication, 25 lbs and Over, 6 count
PetArmor FastCaps (nitenpyram) Oral Flea Control Medication, 25 lbs and Over, 6 count
Best Tablet for Large Dogs
Price not available
For larger dogs, different levels of medication are necessary. This dose will get the job done. It will kill. However, it won’t protect.
Advantus (Imidacloprid) Chewable Flea Treatment for Small Dogs, 7 Count, 4-22 Pounds
Advantus (Imidacloprid) Chewable Flea Treatment for Small Dogs, 7 Count, 4-22 Pounds
Best Soft Chew for Small Dogs
$28.98
Soft chews are a much more pleasant way to feed medicine to your dog. We love this formula and how much dogs love it.

Last update on 2023-06-03 / Affiliate links / Images from Amazon Product Advertising API

How We Found the Best Oral Flea Medicine for Dogs
8 Reviewers
35 Products Considered
12 Hours of Research
4 Products Reviewed
3 Top Picks
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Best Oral Flea Medicine for Dogs

When you have learned your dog has a flea infestation, you need to take quick action before the problem grows larger and harder to tackle. There are many different treatments available, and one of those treatments is oral medication.

An alternative to topical treatments such as shampoos and sprays, oral medication is fed to your pup. The active ingredients are safe for your furry friend but highly deadly to fleas. When a flea bites a dog who has been eating oral flea medicine, they are sure to die.

Below are a few of what we think are the best oral flea medications for your dogs. Read on to learn more and take action.

Pros
  • Kills on contact
  • Waterproof after 24 hours
  • Kills full life cycle of fleas
Cons
  • Can cause irritation or allergic reactions
  • Inconsistent effectiveness
  • Liquid product can get messy
Features & Specs
  • Active ingredients: Nitenpyram
  • 6 monthly doses
  • Suitable for dogs 11-20 lbs
  • 22.7 grams per tube
  • Gluten free
Pros
  • Effective formula
  • Kills adult fleas
  • Single dose is enough
  • Safe for old or pregnant dogs
  • No Odor
  • No Mess
Cons
  • Not for prevention
  • Does not attack eggs
Features & Specs
  • Active ingredients: Nitenpyram
  • 6 tablets per pack
  • For dogs 25 pounds and up
  • Use on dogs 4 weeks or older
  • Starts working in 30 minutes
Service worker

Trying to get rid of fleas for good?

Get a FREE Quote & BEST PRICE from a local exterminator

(866) 470-1609
  • Available Next Day
  • No Obligation Assessment
  • Guarantee Results
Pros
  • Soft chew tastes good to dogs
  • Fast-working formula
  • Effectively kills biting fleas
  • Over the counter
  • Safe for daily treatments
  • Safe for dogs with animal protein allergies
Cons
  • Not safe for children
Features & Specs
  • Active ingredients: Imidacloprid
  • 7 soft chews per box (Available in 30)
  • 7.5mg
  • Use on dogs 10 weeks and older
  • For dogs 4 to 22 pounds
  • Starts working within 1 hour
Pros
  • Starts killing fast
  • Kills adult fleas through biting
  • Savory flavor
  • Soft chews
  • Over the counter
  • Okay for dogs with animal protein food allergy
  • Easy to use
Cons
  • Not for prevention
  • Not safe for children
Features & Specs
  • Active ingredients: Imidacloprid
  • 37.5mg
  • 7 chews per pack (Available in 30)
  • For dogs 23 to 110 pounds
  • Use on dogs 10 weeks or older
Seresto Cat Flea Collar

Seresto Cat Flea Collar

| Updated for 2021Overall Rating: ProsLong-lasting protectionRemoves the need for any other treatmentsKills bugs before they can bite ConsCan cause allergic...

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Service worker

Trying to get rid of fleas for good?

Get a FREE Quote & BEST PRICE from a local exterminator

(866) 470-1609
  • Available Next Day
  • No Obligation Assessment
  • Guarantee Results
Service worker

Trying to get rid of fleas for good?

Get a FREE Quote & BEST PRICE from a local exterminator

(866) 470-1609
  • Available Next Day
  • No Obligation Assessment
  • Guarantee Results

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